Skip Navigation

Human Molecular Genetics 2008 17(R1):R28-R36; doi:10.1093/hmg/ddn149
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Lunyak, V. V.
Right arrow Articles by Rosenfeld, M. G.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lunyak, V. V.
Right arrow Articles by Rosenfeld, M. G.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2008. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

This article appears in the following Human Molecular Genetics issue: Stem Cells and Regeneration [View the issue table of contents]

Epigenetic regulation of stem cell fate

Victoria V. Lunyak1,* and Michael G. Rosenfeld2

1 Buck Institute for Age Research, 8001 Redwood Blvd, Novato, CA 94945, USA 2 Howard Hughes Medical Institute, Department of Molecular Medicine, School of Medicine, University of California, 9500 Gilman Drive, Rm 345, La Jolla, San Diego, CA 92093-0648, USA

* To whom correspondence should be addressed. Tel: +1 4152092000; Fax: +1 4158991810; Email: vlunyak{at}buckinstitute.org

Received February 13, 2008; Revised April 18, 2008; Accepted May 2, 2008

Stem cell-based regenerative medicine holds great promise for repair of diseased tissue. Modern directions in the field of epigenetic research aimed to decipher the epigenetic signals that give stem cells their unique ability to self-renew and differentiate into different cell types. However, this research is only the tip of the iceberg when it comes to writing an ‘epigenetic instruction manual’ for the ramification of molecular details of cell commitment and differentiation. In this review, we discuss the impact of the epigenetic research on our understanding of stem cell biology.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.