Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (63)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Kvaløy, K.
Right arrow Articles by Brown, W.R.A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kvaløy, K.
Right arrow Articles by Brown, W.R.A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1994 Oxford University Press

OTHER

The sequence organization of the long arm pseudoautosomal region of the human sex chromosomes

K. Kvaløy, F. Galvagni and W.R.A. Brown*

Department of Biochemistry, University of Oxford South Parks Road, Oxford 0X1 3QU, UK

* To whom correspondence should be addressed

Received February 14, 1994; Accepted March 14, 1994

We have analysed the sequence organization of the pseudoautosomal region at the telomeres of the long arms of the human sex chromosomes and shown that It is 320 kb long. A LINE sequence Is present on both the X and Y chromosomes immediately adjacent to the breakpoint in homology suggesting that the homology arose as a result of an ectopic recombination event mediated by LINE sequences originally present in non-homologous stretches of X and Y chromosomal DNA. This led to the translocatlon of sequences from the X chromosome telomere onto the Y chromosome and created a new pseudoautosomal region.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J AndrolHome page
L. Yogev, S. Segal, E. Zeharia, R. Gamzu, B. B. Maymon, G. Paz, A. Botchan, R. Hauser, H. Yavetz, and S. E. Kleiman
Sex Chromosome Alignment at Meiosis of Azoospermic Men With Azoospermia Factor Microdeletion
J Androl, January 1, 2004; 25(1): 110 - 116.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
F. J. Charchar, M. Svartman, N. El-Mogharbel, M. Ventura, P. Kirby, M. R. Matarazzo, A. Ciccodicola, M. Rocchi, M. D'Esposito, and J. A. M. Graves
Complex Events in the Evolution of the Human Pseudoautosomal Region 2 (PAR2)
Genome Res., February 1, 2003; 13(2): 281 - 286.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
J. Perry, S. Palmer, A. Gabriel, and A. Ashworth
A Short Pseudoautosomal Region in Laboratory Mice
Genome Res., November 1, 2001; 11(11): 1826 - 1832.
[Abstract] [Full Text] [PDF]

Home page
 Hum Mol GenetHome page
N. S. Thomas, S. Ennis, A. J. Sharp, M. Durkie, T. J. Hassold, A. R. Collins, and P. A. Jacobs
Maternal sex chromosome non-disjunction: evidence for X chromosome-specific risk factors
Hum. Mol. Genet., February 1, 2001; 10(3): 243 - 250.
[Abstract] [Full Text] [PDF]

Home page
 Hum Mol GenetHome page
A. Ciccodicola, M. D'Esposito, T. Esposito, F. Gianfrancesco, C. Migliaccio, M. G. Miano, M. R. Matarazzo, M. Vacca, A. Franze, M. Cuccurese, et al.
Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region
Hum. Mol. Genet., February 12, 2000; 9(3): 395 - 401.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
U C Rogner, N S Heiss, P Kioschis, S Wiemann, B Korn, and A Poustka
Transcriptional analysis of the candidate region for incontinentia pigmenti (IP2) in Xq28.
Genome Res., October 1, 1996; 6(10): 922 - 934.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.