Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (33)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Tribioli, C.
Right arrow Articles by Tonlolo, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Tribioli, C.
Right arrow Articles by Tonlolo, D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1994 Oxford University Press

OTHER

Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae

C. Tribioli1, M. Mancini1, E. Plassart1, S. Bione1, S. Rivella1, C. Sala2, G. Torri1,2 and D. Tonlolo1,*

1Istituto di Genetica Biochimica ed Evoluzionistica, CNR Via Abbiategrasso 207, 27100 Pavia, Milano, Italy 2DIBIT-HSR Via Olgettina 60, Milano, Italy

*To when correspondence should be addressed

Received February 11, 1994; Revised April 27, 1994; Accepted April 27, 1994

In this paper, we describe the physical and transcriptional organization of a region of 140 kb in Xq28, 5' to the L1CAM gene. By isolation and mapping of CpG islands to the physical map of the region, isolation of cDNAs, determination of partial nucleotide sequences and study of the pattern of expression and of the orientation of the transcripts identified we have established a transcriptional map of this region. In this map, previously identified genes (L1CAM, V2R, HCF1 and RnBP) have been positioned as well as 3 new genes. All genes in the region are rather small, ranging in size from 2 to 30 kb, and very close to one another. With the exception of the V2R gene, they are housekeeping, have a CpG island at their 5' end and the same orientation of transcription. This kind of organization is consistent with the one previously described for the more distal portion of Xq28, between the Color Vision (CV) and the G6PD genes and indicates that genes with housekeeping and tissue specific pattern of expression are interspersed in the genome but they are probably found in different ‘transcriptional domains’. Among the new genes, TE2 demonstrated 40% identity with the protein N-acetyl transferase ARD1 of S.cerevisiae: TE2 may be the human homologue of the S.cerevisiae gene.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Mol. Cell. Biol.Home page
K. K. Starheim, D. Gromyko, R. Evjenth, A. Ryningen, J. E. Varhaug, J. R. Lillehaug, and T. Arnesen
Knockdown of Human N{alpha}-Terminal Acetyltransferase Complex C Leads to p53-Dependent Apoptosis and Aberrant Human Arl8b Localization
Mol. Cell. Biol., July 1, 2009; 29(13): 3569 - 3581.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
T. S. Fisher, S. D. Etages, L. Hayes, K. Crimin, and B. Li
Analysis of ARD1 Function in Hypoxia Response Using Retroviral RNA Interference
J. Biol. Chem., May 6, 2005; 280(18): 17749 - 17757.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
S. Bione, F. Rizzolio, C. Sala, R. Ricotti, M. Goegan, M.C. Manzini, R. Battaglia, A. Marozzi, W. Vegetti, L. Dalpra, et al.
Mutation analysis of two candidate genes for premature ovarian failure, DACH2 and POF1B
Hum. Reprod., December 1, 2004; 19(12): 2759 - 2766.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
L. Carrel, A. A. Cottle, K. C. Goglin, and H. F. Willard
From the Cover: A first-generation X-inactivation profile of the human X chromosome
PNAS, December 7, 1999; 96(25): 14440 - 14444.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
L. Carrel and H. F. Willard
Heterogeneous gene expression from the inactive X chromosome: An X-linked gene that escapes X inactivation in some human cell lines but is inactivated in others
PNAS, June 22, 1999; 96(13): 7364 - 7369.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
I. Maru, Y. Ohta, K. Murata, and Y. Tsukada
Molecular Cloning and Identification of N-Acyl-D-glucosamine 2-Epimerase from Porcine Kidney as a Renin-binding Protein
J. Biol. Chem., July 5, 1996; 271(27): 16294 - 16299.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.