Skip Navigation

Human Molecular Genetics 2006 15(4):665; doi:10.1093/hmg/ddi488
This Article
Right arrow Extract Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Bett, J. S.
Right arrow Articles by Bates, G. P.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Bett, J. S.
Right arrow Articles by Bates, G. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2006. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

CORRIGENDUM

Proteasome impairment does not contribute to pathogenesis in R6/2 Huntington's disease mice: exclusion of proteasome activator REG{gamma} as a therapeutic target

John S. Bett, Geoffrey M. Goellner, Ben Woodman, Gregory Pratt, Martin Rechsteiner and Gillian P. Bates

Human Molecular Genetics (2006) 15, 33–44; doi:10.1093/hmg/ddi423

This figure has been reproduced as a corrigendum because the upper and lower panels of Figure 2B were blank in the original publication of this paper.


Figure 4881
View larger version (68K):
[in this window]
[in a new window]
  		Figure 2. REG{gamma} is highly expressed in the mouse brain and is restricted to neuronal nuclei. (A) Coronal sections through cortex of WT and REG{gamma} null mouse brain reveal a predominant nuclear localization of REG{gamma}. The absence of any specific staining in the null mice confirms that REG{gamma} has been successfully knocked out and that the antibody is specific. Arrow points to a nucleus expressing REG{gamma}, and inset shows higher magnification of another nucleus expressing REG{gamma}. The nuclear counterstain is methyl green. (B) Western blot analysis on nuclear and cytoplasmic 12-week-old brain fractions confirms that REG{gamma} has a nuclear localizati on. Blots were stained with histone H2B as a nuclear marker and ß-actin as a cytoplasmic marker. (C) REG{gamma} colocalizes with the neuronal marker NeuN in the mouse brain. No REG{gamma} was detected in glial cells. Ctx, cortex; cyt, cytoplasm and nuc, nucleus.

 

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?



This Article
Right arrow Extract Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Bett, J. S.
Right arrow Articles by Bates, G. P.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Bett, J. S.
Right arrow Articles by Bates, G. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?