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Human Molecular Genetics Advance Access published online on February 24, 2006
Human Molecular Genetics, doi:10.1093/hmg/ddl029
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© The Author 2006. Published by Oxford University Press. All rights reserved
Received November 10, 2005
Revised February 10, 2006
Accepted February 10, 2006

Article

Strength of the purifying selection against different categories of the point mutations in the coding regions of the human genome

Ivan P. Gorlov 1 *, Marek Kimmel 2, and Christopher I. Amos 3

1 Department of Epidemiology, Unit 340, The University of Texas M. D. Anderson Cancer Center, Houston, 1515 Holcombe Boulevard, TX 77030
2 Department of Statistics, Rice University, Houston, TX
3 Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, TX

* To whom correspondence should be addressed.
Ivan P. Gorlov, E-mail: ipgorlov{at}mdanderson.org



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