Human Molecular Genetics

SPECIAL SERIES: MICROARRAY REPORTS:

Harry T. Orr

Microarrays and polyglutamine disorders: reports from the Hereditary Disease Array Group
Hum. Mol. Genet. 2002 11: 1909-1910; doi:10.1093/hmg/11.17.1909 [Extract] [FREE Full Text] [PDF] [Request Permissions]  

Ruth Luthi-Carter, Sarah A. Hanson, Andrew D. Strand, Donald A. Bergstrom, Wanjoo Chun, Nikki L. Peters, Annette M. Woods, Edmond Y. Chan, Charles Kooperberg, Dimitri Krainc, Anne B. Young, Stephen J. Tapscott, and James M. Olson

Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain
Hum. Mol. Genet. 2002 11: 1911-1926; doi:10.1093/hmg/11.17.1911 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ruth Luthi-Carter, Andrew D. Strand, Sarah A. Hanson, Charles Kooperberg, Gabriele Schilling, Albert R. La Spada, Diane E. Merry, Anne B. Young, Christopher A. Ross, David R. Borchelt, and James M. Olson

Polyglutamine and transcription: gene expression changes shared by DRPLA and Huntington's disease mouse models reveal context-independent effects
Hum. Mol. Genet. 2002 11: 1927-1937; doi:10.1093/hmg/11.17.1927 [Abstract] [FREE Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Edmond Y.W. Chan, Ruth Luthi-Carter, Andrew Strand, Steven M. Solano, Sarah A. Hanson, Molly M. DeJohn, Charles Kooperberg, Kathryn O. Chase, Marian DiFiglia, Anne B. Young, Blair R. Leavitt, Jang-Ho J. Cha, Neil Aronin, Michael R. Hayden, and James M. Olson

Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease
Hum. Mol. Genet. 2002 11: 1939-1951; doi:10.1093/hmg/11.17.1939 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Simonetta Sipione, Dorotea Rigamonti, Marta Valenza, Chiara Zuccato, Luciano Conti, Joel Pritchard, Charles Kooperberg, James M. Olson, and Elena Cattaneo

Early transcriptional profiles in huntingtin-inducible striatal cells by microarray analyses
Hum. Mol. Genet. 2002 11: 1953-1965; doi:10.1093/hmg/11.17.1953 [Abstract] [FREE Full Text] [PDF] [Supplementary Data] [Request Permissions]  

Andrew P. Lieberman, George Harmison, Andrew D. Strand, James M. Olson, and Kenneth H. Fischbeck

Altered transcriptional regulation in cells expressing the expanded polyglutamine androgen receptor
Hum. Mol. Genet. 2002 11: 1967-1976; doi:10.1093/hmg/11.17.1967 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Xie L. Xu, James M. Olson, and Lue Ping Zhao

A regression-based method to identify differentially expressed genes in microarray time course studies and its application in an inducible Huntington's disease transgenic model
Hum. Mol. Genet. 2002 11: 1977-1985; doi:10.1093/hmg/11.17.1977 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

ARTICLES:

Xavier Estivill, Joseph Cheung, Miguel Angel Pujana, Kazuhiko Nakabayashi, Stephen W. Scherer, and Lap-Chee Tsui

Chromosomal regions containing high-density and ambiguously mapped putative single nucleotide polymorphisms (SNPs) correlate with segmental duplications in the human genome
Hum. Mol. Genet. 2002 11: 1987-1995; doi:10.1093/hmg/11.17.1987 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Benjamin G. Challis, Lynn E. Pritchard, John W.M. Creemers, Jerome Delplanque, Julia M. Keogh, Jian'an Luan, Nicholas J. Wareham, Giles S.H. Yeo, Sumit Bhattacharyya, Phillipe Froguel, Anne White, I. Sadaf Farooqi, and Stephen O'Rahilly

A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism
Hum. Mol. Genet. 2002 11: 1997-2004; doi:10.1093/hmg/11.17.1997 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Wei-Li Di, James Monypenny, John E.A. Common, Cameron T.C. Kennedy, Katalin A. Holland, Irene M. Leigh, Elizabeth L. Rugg, Daniel Zicha, and David P. Kelsell

Defective trafficking and cell death is characteristic of skin disease-associated connexin 31 mutations
Hum. Mol. Genet. 2002 11: 2005-2014; doi:10.1093/hmg/11.17.2005 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

David-Alexandre Tregouet, Sandrine Barbaux, Sylvie Escolano, Nadia Tahri, Jean-Louis Golmard, Laurence Tiret, and François Cambien

Specific haplotypes of the P-selectin gene are associated with myocardial infarction
Hum. Mol. Genet. 2002 11: 2015-2023; doi:10.1093/hmg/11.17.2015 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Ulrich Mühlenhoff, Nadine Richhardt, Michael Ristow, Gyula Kispal, and Roland Lill

The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins
Hum. Mol. Genet. 2002 11: 2025-2036; doi:10.1093/hmg/11.17.2025 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Yvonne Hofmann and Brunhilde Wirth

hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-ß1
Hum. Mol. Genet. 2002 11: 2037-2049; doi:10.1093/hmg/11.17.2037 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Mireille Castanet, Soo-Mi Park, Aaron Smith, Michel Bost, Juliane Léger, Stanislas Lyonnet, Anna Pelet, Paul Czernichow, Krishna Chatterjee, and Michel Polak

A novel loss-of-function mutation in TTF-2 is associated with congenital hypothyroidism, thyroid agenesis and cleft palate
Hum. Mol. Genet. 2002 11: 2051-2059; doi:10.1093/hmg/11.17.2051 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

Janine Kirby, Fiona M. Menzies, Mark R. Cookson, Katherine Bushby, and Pamela J. Shaw

Differential gene expression in a cell culture model of SOD1-related familial motor neurone disease
Hum. Mol. Genet. 2002 11: 2061-2075; doi:10.1093/hmg/11.17.2061 [Abstract] [FREE Full Text] [PDF] [Request Permissions]  

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