Cover: The background photograph depicts BrdU incorporation in the neuroepithelium of a 10.5-day-old transgenic embryo overexpressing the human ATRX protein. The inset photograph demonstrates the wide range of early developmental defects observed in litters killed at E9.5 when an ATRX transgenic male is bred with a wild-type female. See Article by Bérubé et al., in this issue, pp. 253-261.
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