Cover: Mouse embryo (10.5 days post-conception) showing the normal development of an elaborate extra-embryonic vascular network. The article describes how fetal modifier genes interact with maternal genetic background to influence vascular development of Tgfb1-/- knock out mice, with relevance to several human vascular diseases including hereditary hemorrhagic telangiectasia. See Article by Tang et al., in this issue, pp.1579-1589.
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