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Cover:Immunofluorescence confocal micrograph showing the distribution of polymerized microtubules (red) in Cos-7 cells transfected with the GFP-tagged endosomal protein CHMP1B (green). There is no gross effect of CHMP1B on the microtubule architecture. CHMP1B is a binding partner of the hereditary spastic paraplegia protein spastin, which has been implicated in microtubule regulation. See Article by Reid et al., in this issue, pp. 19-38.

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