Cover: The figure shows the predicted 3D structure of the trimeric serine protease Omi/HtrA2. The predicted structure is based on X-ray data published by Yigong Shi (NSB 22 April 2002, doi:10.1038/nsb795). The active center of the serine protease (S306) and two amino acids that were identified in the accompanying paper by Strauss and colleagues to show a polymorphism (A141S) or mutation (G399S) in Parkinson's disease patients are highlighted in green and purple, respectively. See article by Strauss et al., in this issue, pp. 2099–2111.
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