Human Molecular Genetics

ARTICLES:

Steve Dorus, Jeffrey R. Anderson, Eric J. Vallender, Sandra L. Gilbert, Li Zhang, Leona G. Chemnick, Oliver A. Ryder, Weimin Li, and Bruce T. Lahn

Sonic Hedgehog, a key development gene, experienced intensified molecular evolution in primates
Human Molecular Genetics Advance Access published on May 10, 2006
Hum. Mol. Genet. 2006 15: 2031-2037; doi:10.1093/hmg/ddl123 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

George Xinarianos, Fiona E. McRonald, Janet M. Risk, Naomi L. Bowers, Georgios Nikolaidis, John K. Field, and Triantafillos Liloglou

Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in non-small cell lung cancer
Human Molecular Genetics Advance Access published on May 12, 2006
Hum. Mol. Genet. 2006 15: 2038-2044; doi:10.1093/hmg/ddl128 [Abstract] [Full Text] [PDF] [Request Permissions]  

J. Menéndez, J.A. Rodríguez-Navarro, R.M. Solano, M.J. Casarejos, I. Rodal, R. Guerrero, M.P. Sánchez, J. Avila, M.A. Mena, and J.G. de Yébenes

Suppression of Parkin enhances nigrostriatal and motor neuron lesion in mice over-expressing human-mutated tau protein
Human Molecular Genetics Advance Access published on May 12, 2006
Hum. Mol. Genet. 2006 15: 2045-2058; doi:10.1093/hmg/ddl129 [Abstract] [Full Text] [PDF] [Request Permissions]  

Cornelia Hampe, Hector Ardila-Osorio, Margot Fournier, Alexis Brice, and Olga Corti

Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin–protein ligase with monoubiquitylation capacity
Human Molecular Genetics Advance Access published on May 19, 2006
Hum. Mol. Genet. 2006 15: 2059-2075; doi:10.1093/hmg/ddl131 [Abstract] [Full Text] [PDF] [Request Permissions]  

Qing-Peng Kong, Hans-Jürgen Bandelt, Chang Sun, Yong-Gang Yao, Antonio Salas, Alessandro Achilli, Cheng-Ye Wang, Li Zhong, Chun-Ling Zhu, Shi-Fang Wu, Antonio Torroni, and Ya-Ping Zhang

Updating the East Asian mtDNA phylogeny: a prerequisite for the identification of pathogenic mutations
Human Molecular Genetics Advance Access published on May 19, 2006
Hum. Mol. Genet. 2006 15: 2076-2086; doi:10.1093/hmg/ddl130 [Abstract] [Full Text] [PDF] [Supplementary Material] [Request Permissions]  

Xiaoyan Lin, Jill W. Miller, Ami Mankodi, Rahul N. Kanadia, Yuan Yuan, Richard T. Moxley, Maurice S. Swanson, and Charles A. Thornton

Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy
Human Molecular Genetics Advance Access published on May 22, 2006
Hum. Mol. Genet. 2006 15: 2087-2097; doi:10.1093/hmg/ddl132 [Abstract] [Full Text] [PDF] [Supplementary Material] [Request Permissions]  

John A. Bernat, Gregory E. Crawford, Aleksey Y. Ogurtsov, Francis S. Collins, David Ginsburg, and Alexey S. Kondrashov

Distant conserved sequences flanking endothelial-specific promoters contain tissue-specific DNase-hypersensitive sites and over-represented motifs
Human Molecular Genetics Advance Access published on May 24, 2006
Hum. Mol. Genet. 2006 15: 2098-2105; doi:10.1093/hmg/ddl133 [Abstract] [Full Text] [PDF] [Supplementary Material] [Request Permissions]  

Joshua M. Akey, Willie J. Swanson, Jennifer Madeoy, Michael Eberle, and Mark D. Shriver

TRPV6 exhibits unusual patterns of polymorphism and divergence in worldwide populations
Human Molecular Genetics Advance Access published on May 22, 2006
Hum. Mol. Genet. 2006 15: 2106-2113; doi:10.1093/hmg/ddl134 [Abstract] [Full Text] [PDF] [Supplementary Material] [Request Permissions]  

Urvee A. Desai, Judit Pallos, Aye Aye K. Ma, Brent R. Stockwell, Leslie Michels Thompson, J. Lawrence Marsh, and Marc I. Diamond

Biologically active molecules that reduce polyglutamine aggregation and toxicity
Human Molecular Genetics Advance Access published on May 23, 2006
Hum. Mol. Genet. 2006 15: 2114-2124; doi:10.1093/hmg/ddl135 [Abstract] [Full Text] [PDF] [Supplementary Material] [Request Permissions]  

Miho Kawamura-Saito, Yukari Yamazaki, Keiko Kaneko, Noriyoshi Kawaguchi, Hiroaki Kanda, Hiroyuki Mukai, Takahiro Gotoh, Tohru Motoi, Masashi Fukayama, Hiroyuki Aburatani, Toichiro Takizawa, and Takuro Nakamura

Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation
Human Molecular Genetics Advance Access published on May 22, 2006
Hum. Mol. Genet. 2006 15: 2125-2137; doi:10.1093/hmg/ddl136 [Abstract] [Full Text] [PDF] [Request Permissions]  

María de Haro, Ismael Al-Ramahi, Beatrice De Gouyon, Lubna Ukani, Alberto Rosa, Nuno André Faustino, Tetsuo Ashizawa, Thomas A. Cooper, and Juan Botas

MBNL1 and CUGBP1 modify expanded CUG-induced toxicity in a Drosophila model of myotonic dystrophy type 1
Human Molecular Genetics Advance Access published on May 24, 2006
Hum. Mol. Genet. 2006 15: 2138-2145; doi:10.1093/hmg/ddl137 [Abstract] [Full Text] [PDF] [Supplementary Material] [Request Permissions]  

Jichao Chen, Amir Rattner, and Jeremy Nathans

Effects of L1 retrotransposon insertion on transcript processing, localization and accumulation: lessons from the retinal degeneration 7 mouse and implications for the genomic ecology of L1 elements
Human Molecular Genetics Advance Access published on May 24, 2006
Hum. Mol. Genet. 2006 15: 2146-2156; doi:10.1093/hmg/ddl138 [Abstract] [Full Text] [PDF] [Request Permissions]  

Marilena D'Aurelio, Carl D. Gajewski, Giorgio Lenaz, and Giovanni Manfredi

Respiratory chain supercomplexes set the threshold for respiration defects in human mtDNA mutant cybrids
Human Molecular Genetics Advance Access published on June 1, 2006
Hum. Mol. Genet. 2006 15: 2157-2169; doi:10.1093/hmg/ddl141 [Abstract] [Full Text] [PDF] [Request Permissions]  

Ryozo Kuwano, Akinori Miyashita, Hiroyuki Arai, Takashi Asada, Masaki Imagawa, Mikio Shoji, Susumu Higuchi, Katsuya Urakami, Akiyoshi Kakita, Hitoshi Takahashi, Tamao Tsukie, Shinichi Toyabe, Kohei Akazawa, Ichiro Kanazawa, Yasuo Ihara, and The Japanese Genetic Study Consortium for Alzheimer's Disease

Dynamin-binding protein gene on chromosome 10q is associated with late-onset Alzheimer's disease
Human Molecular Genetics Advance Access published on June 1, 2006
Hum. Mol. Genet. 2006 15: 2170-2182; doi:10.1093/hmg/ddl142 [Abstract] [Full Text] [PDF] [Supplementary Data] [Request Permissions]  

CORRIGENDA:

Caroline Kappeler, Yoann Saillour, Jean-Pierre Baudoin, Françoise Phan Dinh Tuy, Chantal Alvarez, Christophe Houbron, Patricia Gaspar, Ghislaine Hamard, Jamel Chelly, Christine Métin, and Fiona Francis

Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice
Hum. Mol. Genet. 2006 15: 2183; doi:10.1093/hmg/ddl139 [Extract] [Full Text] [PDF] [Request Permissions]  

Gary Temple, Philippe Lamesch, Stuart Milstein, David E. Hill, Lukas Wagner, Troy Moore, and Marc Vidal

From genome to proteome: developing expression clone resources for the human genome
Hum. Mol. Genet. 2006 15: 2184; doi:10.1093/hmg/ddl140 [Extract] [Full Text] [PDF] [Request Permissions]  

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