Cover: The cover images shows Safranin O staining of the articular surface of the knee joints at 16 months of age showing severe articular cartilage degradation associated with a complete loss of sulphated proteoglycans in mice homozygous for the C-terminal COMP mutation. The panels from left to right indicate: wild-type; heterozygous for the mutation and homozygous for the mutation. See
Pirog-Garcia et al., pp. 2072-2088, this issue, for more information.
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