Cover: The cover figure shows Mutations in DNA methyltransferase 3B (DNMT3B) result in large-scale alterations in gene expression patterns. Principal Component Analysis (PCA) of global expression profiles in ICF syndrome (hypomorphic mutations in DNMT3B) and normal lymphoblastoid cell lines (LCLs). Data was generated using the Affymetrix U133A and U133B GeneChip set and LCLs derived from five normal and three ICF syndrome individuals (represented by the colored balls). For further information, see B. Jin et al., pp. 690-709.
[Table of Contents]